This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.
Hereditary breast and ovarian cancer [23 genes]
The most frequent causes of hereditary breast and ovarian cancer are germinal variants in the BRCA1and BRCA2 tumor suppressors. Likewise, other high-moderate penetrance genes exist, whose genetic effects lead to a predisposition to develop breast and ovarian cancer, such as TP53, PTEN, ATM, PALB2, and CDH1, among others.
- Our experts recommend studying the predisposition for breast/ovarian syndrome through our general panel. Guided analysis in individuals who are of Ashkenazi Jew origin can be considered by starting with BRCA1 and BRCA2. Also, we offer the possibility of evaluating individually each of the genes in the panel.
Request study
Informed consent
Steps to follow
Ask for information
Steps to follow
How to order
1. Download & fill out
Please cover as many fields as possible in both documents
2. Sample collection
Three sample types: saliva, peripheral blood or genomic DNA
3. Pack the sample
Please pack the sample in a way to prevent leakage
4. Send the sample & the request
Please schedule the delivery for Mon–Thur: 8am – 5pm
5. Result: the report
Via: Client Site HIC / Client Site Imegen / Certified email
Solicita información de
Hereditary breast and ovarian cancer
Turnaround time (TAT): 4 weeks
Ref. S-202009121
Hereditary breast and ovarian cancer: View panel
- MLH1
- MSH2
- MSH6
- BRCA1
- BRCA2
- CDH1
- NF1
- TP53
- STK11
- ATM
- RAD51C
- PMS2
- PTEN
- PALB2
- EPCAM
- NBN
- MRE11
- BARD1
- RAD51D
- RAD50
- CHEK2
- BRIP1
- XRCC2
Priority Genes : Genes where there is sufficient evidence (clinical and functional) to consider them associated with the disease; they are included in the clinical practice guidelines.
Secondary Genes: Genes related to the disease, but with a lower level of evidence or that constitute sporadic cases.
* Candidate Genes: Not enough evidence in humans, but potentially associated with the disease.