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Hereditary renal cancer [7 genes]
Even though the majority of renal carcinomas are sporadic, there are hereditary syndromes that are associated to its predisposition, such as Von Hippel-Lindau syndrome (due to mutations in the VHL gene), Birt-Hogg-Dubé syndrome (FLCN gene), hereditary papillary renal cell carcinoma (MET gene), and hereditary leiomyomatosis associated with carcinoma of the renal cells (LH gene).
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Steps to follow
Ask for information
Steps to follow
How to order
1. Download & fill out
Please cover as many fields as possible in both documents
2. Sample collection
Three sample types: saliva, peripheral blood or genomic DNA
3. Pack the sample
Please pack the sample in a way to prevent leakage
4. Send the sample & the request
Please schedule the delivery for Mon–Thur: 8am – 5pm
5. Result: the report
Via: Client Site HIC / Client Site Imegen / Certified email
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Hereditary renal cancer
Turnaround time (TAT): 4 weeks
Ref. S-202009675
Hereditary renal cancer: View panel
The genetic study can help carry out a correct differential diagnosis of the pathology and, therefore, not only guide the treatment but also provide a better prognosis approximation. Our recommendation includes a panel of multiple genes taking into account the different syndromes associated with both hereditary prostate cancer and hereditary renal cancer.
- MET
- VHL
- FH
- SDHB
- SDHA
- FLCN
- BAP1
Priority Genes : Genes where there is sufficient evidence (clinical and functional) to consider them associated with the disease; they are included in the clinical practice guidelines.
Secondary Genes: Genes related to the disease, but with a lower level of evidence or that constitute sporadic cases.
* Candidate Genes: Not enough evidence in humans, but potentially associated with the disease.