HyperCKemia and rhabdomyolysis panel [47 genes]

Persistent elevation in creatine phosphokinase (CPK) can be a marker of mild muscular disease, or its early stages, and represents a frequent cause of referral to a neuromuscular specialist. On the other hand, rhabdomyolisis is the result of sudden tearing of muscle fibers and the release of cell content into the bloodstream, generating an increase in CPK of at least 10 fold, to later decrease rapidly. This process can be accompanied by the secretion of myoglobin in urine, giving it a dark color tone. This panel includes genes related to structural-type muscular disease as well as metabolic-type muscular diseases that may present like this.